Taladafilo: An Unfamiliar Term in Need of Explanation

The question you want to ask may be "tadalafil".

1. Basic information

1、pharmacological effects

- Tadalafil is a selective and reversible inhibitor of cyclic guanosine phosphate (cGMP)-specific phosphodiesterase 5 (PDE5). By inhibiting PDE5, it increases cGMP levels in the corpus cavernosum, relaxes smooth muscle, and flows into the corpus cavernosum, thereby promoting penile erection and is used to treat male erectile dysfunction (ED).

2、characteristics of drugs

- Tadalafil has a long-lasting effect and is often referred to as "weekend pills". Compared with some other drugs for the treatment of ED, it can act for as long as 36 hours. During this time period, patients are sexually stimulated. It may be easier to obtain and maintain an erection.

2. Clinical application

1、erectile dysfunction treatment

- The appropriate dose can be adjusted according to the patient's specific conditions, such as the severity of the condition, age, comorbidities and other factors. Common doses include different specifications such as 5mg, 10mg, and 20mg. They are taken as needed before sexual activity. There are also low doses (such as 5mg per day) to achieve long-term improvement of erectile function.

2、Studies on other potential uses

- There are also some studies on tadalafil in the treatment of pulmonary hypertension. The principle is to dilate pulmonary vessels, reduce pulmonary vascular resistance, and improve the hemodynamic status of patients with pulmonary hypertension.