Dadalafilo or Tadalafil/Cialis: Spelling Query
Gui í a de Salud Masculina
tadalafil (tadalafil) and Cialis (Sirex) are actually the same drug.
Basic information
Drug type
Tadalafil is a type 5 phosphodiesterase (PDE5) inhibitor used in the treatment of male erectile dysfunction (ED).
Mechanism of action
During sexual stimulation, neurons in the cavernous body of the penis release nitric oxide (NO). NO activates guanylate cyclase and increases the level of cyclic guanosine monophosphate (cGMP), resulting in relaxation of smooth muscle in the corpus cavernosum and blood flow into the penile tissue, resulting in an erection.
PDE5 will decompose cGMP and decrease its concentration, leading to erection regression. Tadalafil helps to maintain penile erectile function by inhibiting the activity of PDE5 and increasing the concentration of cGMP.
Drug characteristics
Long-term effect
Tadalafil works for a long time, with a half-life of about 17.5 hours, which means that a single dose of tadalafil may improve erectile function for a long time. Small doses of tadalafil (such as 5mg) can be taken regularly daily and can help patients improve erectile function for a continuous period of time, not just for a short period of time.
Effective time
Tadalafil takes effect within 30 minutes to 2 hours after oral administration, but sexual stimulation is needed to produce the effect of erection.
Matters needing attention
intended for
It is mainly suitable for adult male patients with erectile dysfunction, but before using it, the patient should inform the doctor of his or her medical history, especially the history of cardiovascular disease, hypotension, liver and kidney insufficiency, etc.
-because of its mechanism of action on blood vessels, it is prohibited for patients who are taking nitrates (such as nitroglycerin), as combination may lead to severe hypotension.
Adverse reaction
Common adverse reactions include headache, facial flushing, indigestion, nasal congestion, muscle pain, etc. These adverse reactions are usually mild to moderate and will gradually alleviate or disappear after drug metabolism.
Tadalafil is a drug mainly used to treat male erectile dysfunction (ED). It belongs to phosphodiesterase-5 (PDE5) inhibitors. It increases the blood flow of the corpus cavernosum of the penis and helps men achieve and maintain erection by inhibiting the activity of PDE5. One of the trade names of Tadalafil is Cialis.
Cialis (Chinese name: sildenafil) is an oral drug produced by Pfizer for the treatment of male erectile dysfunction. Its mechanism is the same as tadalafil, that is, it increases the blood flow of the corpus cavernosum by inhibiting PDE5 enzyme. Cialis is characterized by fast onset and long duration. It usually begins to act within 30 minutes to 1 hour after taking it, and the effect can last as long as 36 hours.
It should be noted that both tadalafil and Cialis are prescription drugs. Consult your doctor and follow your doctor's advice before use. These drugs may interact with other drugs, so you should inform your doctor of other drugs you are using. For patients with cardiovascular disease, high blood pressure, diabetes and other diseases, special care may be required to use these drugs.
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