Dadalafila 20 mg: Similar to Tadalafil for ED?
Tadalafil 20 mg is a medication commonly used for the treatment of erectile dysfunction (ED) and also for the treatment of symptoms of benign prostatic hyperplasia (BPH) in some cases.
1. Mechanism of action for erectile dysfunction
- Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor. In the penis, sexual stimulation causes the release of nitric oxide (NO). NO activates guanylate cyclase, which increases the levels of cyclic guanosine monophosphate (cGMP). cGMP causes smooth muscle relaxation in the corpus cavernosum of the penis, allowing blood to flow in and resulting in an erection. PDE5 breaks down cGMP. By inhibiting PDE5, tadalafil helps to maintain higher levels of cGMP, facilitating and prolonging erections in response to sexual stimulation.
2. Usage for erectile dysfunction
- It is typically taken as needed, about 30 minutes to several hours before sexual activity. However, it should not be taken more than once a day.
- It is important to note that tadalafil does not cause an erection on its own without sexual stimulation.
3. Usage for benign prostatic hyperplasia
- For BPH, tadalafil helps to relax the smooth muscle in the prostate and bladder neck, which can improve urinary flow and reduce symptoms such as difficulty in starting urination, weak urine stream, and frequent urination. When used for BPH, it is usually taken on a daily basis.
4. Precautions and side effects
Precautions:
- Tadalafil should not be used in combination with nitrates (e.g., nitroglycerin) as this can cause a dangerous drop in blood pressure.
- It may interact with certain medications, so it is important to inform the doctor about all medications being taken, including over - the - counter drugs and herbal supplements.
- Men with certain underlying health conditions such as heart problems, low blood pressure, or liver or kidney disease may need special monitoring or dose adjustments.
Side effects:
- Common side effects may include headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. In some cases, more serious side effects such as vision changes or hearing loss (although rare) may occur. If any unusual or concerning symptoms develop while taking tadalafil, medical attention should be sought immediately.